Structural Biology Center
Home About Us Facilities User Program Resources Research Links Contact Us
links-top_final.gif

Quick Links:

SBC:
APS:
ANL:
Home Pages:

Highlight:

Structure of a symmetric photosynthetic reaction center-photosystem

Structure of a symmetric photosynthetic reaction center-photosystemReaction centers are pigment-protein complexes that drive photosynthesis by converting light into chemical energy. It is believed that they arose once from a homodimeric protein. The symmetry of a homodimer is broken in heterodimeric reaction-center structures, such as those reported previously. The 2.2-angstrom resolution x-ray structure of the homodimeric reaction center-photosystem from the phototroph Heliobacterium modesticaldum exhibits perfect C2 symmetry. The core polypeptide dimer and two small subunits coordinate 54 bacteriochlorophylls and 2 carotenoids that capture and transfer energy to the electron transfer chain at the center, which performs charge separation and consists of 6 (bacterio)chlorophylls and an iron-sulfur cluster; unlike other reaction centers, it lacks a bound quinone. This structure preserves characteristics of the ancestral reaction center, providing insight into the evolution of photosynthesis.

Science. 2017 Sep 8;357(6355):1021-1025.
doi: 10.1126/science.aan5611.
Epub 2017 Jul 27.

 

© 2017 American Association for the Advancement of Science.

  Gisriel C, Sarrou I, Ferlez B, Golbeck JH, Redding KE, Fromme R.

Another SBC Highlight:

Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses

Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses

 

 

Nat Microbiol. 2017 Jun 30;2:17101.
doi: 10.1038/nmicrobiol.2017.101.

Previous SBC Highlights:

 

Highlights featured previously on our web-page

 

ANL and APS Highlights:

 

Highlights featured by either ANL or APS

 

SBC Announcements:

 

ESAF Requirements:

 

When completing your Experimental Safety Approval Form (ESAF), please include the following in your experimental description:

 

APS requests the Experimental Safety Approval Form be submitted at least seven days prior to your scheduled beamtime.

 

Failure to submit your ESAF according to this schedule may result in delaying the beginning of your experiment.

 

 

19-BM Robotic sample mounter available

 

A robot is available for use at beamline 19-BM. The sample dewar accommodates ten Unipuck magazines; pins must be 18mm in length and use either SSRL or ALS bases. Experienced users may now request remote access to 19-BM when applying for beamtime.

 

 

SBC Staff Hosting Changes

 

SBC staff are now available for User Support between the hours of 8:00am and 10:pm.

 

Web Site:

 

Web Site Suggestions?

 

If you have any suggestions or comments, please feel free to e-mail us.

 

Rapid Access Beamtime Available:

SBC Beamtime Request System

The on-line SBC Beamtime Request System allows users to view available beamtime on 19-ID and 19-BM, and to submit a request for rapid beamtime allocation.

Beamtime is available to the research community via a peer reviewed proposal system; it is supported by the U.S. Department of Energy, Office of Biological and Environmental Research.

Current Beamline Statistics:

APS PDB Depositions from BioSync
SBC Sector 19 2015 2016 2017 TOTAL
ID BM ID BM ID BM
PDB Depositions 259 32 219 29 137 17 5128

APS Publications Database:

Publications Total
SBC-CAT Publication List: 19-ID 1538
SBC-CAT Publication List: 19-BM 539
SBC-CAT Publication List: ALL
APS Publications Database

MCSG / APCF Announcements:

 

The Midwest Center for Structural Genomics (MCSG) is accepting applications for access to the scientific facilities and equipment available in Building #446.

 

MCSG's structure determination platform is well established, and combines technologies, robotics and expertise for gene cloning, protein production, and crystallization, as well as biochemical and biophysical characterization.

 

For further information, please contact Andrzej Joachimiak.

 

Future Meetings:

 

CSHL X-ray Methods in Structural Biology Course

October 16-31, 2017

Cold Spring Harbor; New York, USA

 

Advanced Topics in EM Structure Determination: Challenges and Opportunities

October 29 - November 03, 2017

New York; New York, USA

 

CCP4 Study Weekend

January 10-12, 2018

Nottingham; East Midlands, England; UK

 

SBC Beamline Phone Numbers:

Phone Location Number
19-ID Beamline Control Station 630-252-9823
19-ID Beamline Cordless Phone 630-252-0569
19-ID Beamline Inside D-Hutch 630-252-1819
 
19-BM Beamline Control Station 630-252-9833
19-BM Beamline Cordless Phone 630-252-0568
19-BM Beamline Inside D-Hutch 630-252-1719