 The Structural Biology Center (SBC) operates a national user facility for macromolecular crystallography at Sector 19 of the Advanced Photon Source at Argonne National Laboratory. The SBC makes available to scientific community two experimental stations: an insertion-device, 19ID, and a bending-magnet, 19BM and a biochemistry laboratory. SBC beamlines are well suited for a wide range of crystallographic experiments involving:
• Crystals of macromolecular assemblies with very large unit cell
• MAD/SAD phasing
• Crystals of membrane proteins
• Small, weakly diffracting crystals
• Ultra-high resolution crystallography
• Cryo-crystallography
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The SBC mission is to advance and promote scientific and technological innovation in support of the DOE mission by providing world-class scientific research and advancing scientific knowledge:
• SBC provides advanced data collection facilities at the APS to the national user community
andmaintains high-profile user programs
• SBC exploits major advances in macromolecular x-ray crystallography and addresses the most
challenging structural biology problems to advance scientific knowledge
• SBC is an important component of integrated biosciences and contributes to the expansion of existing
programs and exploration of new opportunities in structural biology, proteomics and genomics research
with a major focus on medicine,
bio-nanomachines, and biocatalysis that are highly relevant to energy
resources, health, a clean environment and national security
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